Romidepsin

MedChem Express

Romidepsin [128517-07-7]

10

128517-07-7

Research Use Only

99.98

C24H36N4O6S2

540.70

Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC 50 s of 36 nM, 47 nM, 510 nM and 1.4 microM, respectively [1] . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis [2] .

C/C=C(NC([C@@H](CSSCC/C=C/[C@@H](O1)CC2=O)NC([C@@H](C(C)C)N2)=O)=O)/C(N[C@@H](C(C)C)C1=O)=O

-20°C

12352200