Romidepsin-d7

MedChem Express

Romidepsin-d7

5

Research Use Only

C24H29D7N4O6S2

547.74

Romidepsin-d7 (FK 228-d7) is deuterium labeled Romidepsin. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 microM, respectively[1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis[2].

C/C=C(NC([C@@H](CSSCC/C=C/[C@@H](O1)CC2=O)NC([C@@H](C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N2)=O)=O)/C(N[C@@H](C(C)C)C1=O)=O

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