Roniciclib [1223498-69-8]

TargetMol Chemicals

Roniciclib [1223498-69-8]

9

1223498-69-8

Chemical

Research Use Only

Roniciclib

C18H21F3N4O3S

430.44

Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.

3 years

C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)[S@](=N)(=O)C2CC2)ncc1C(F)(F)F

-20°C

12352200