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ROR alpha antibody [N2N3]

GTX100029
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRORA
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Overview

  • Supplier
    GeneTex
  • Product Name
    ROR alpha antibody [N2N3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6095
  • Target name
    RORA
  • Target description
    RAR related orphan receptor A
  • Target synonyms
    IDDECA; NR1F1; nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; nuclear receptor subfamily 1 group F member 1; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; ROR1; ROR2; ROR3; ROR-alpha; RZRA; RZR-ALPHA; thyroid hormone nuclear receptor alpha variant 4; transcription factor RZR-alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35398
  • Protein Name
    Nuclear receptor ROR-alpha
  • Scientific Description
    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The nuclear receptor RORalpha preserves cardiomyocyte mitochondrial function by regulating caveolin-3-mediated mitophagy. Beak JY et al., 2021 Dec, J Biol Chem
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  • LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling. Luo J et al., 2019 Jun 12, Nat Commun
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  • The nuclear receptor RORalpha protects against angiotensin II-induced cardiac hypertrophy and heart failure. Beak JY et al., 2019 Jan 1, Am J Physiol Heart Circ Physiol
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  • RORalpha and RORgamma expression inversely correlates with human melanoma progression. Brozyna AA et al., 2016 Sep 27, Oncotarget
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