ROR alpha antibody [N2N3]
GTX100029
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRORA
Overview
- SupplierGeneTex
- Product NameROR alpha antibody [N2N3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6095
- Target nameRORA
- Target descriptionRAR related orphan receptor A
- Target synonymsIDDECA; NR1F1; nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; nuclear receptor subfamily 1 group F member 1; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; ROR1; ROR2; ROR3; ROR-alpha; RZRA; RZR-ALPHA; thyroid hormone nuclear receptor alpha variant 4; transcription factor RZR-alpha
- HostRabbit
- IsotypeIgG
- Protein IDP35398
- Protein NameNuclear receptor ROR-alpha
- Scientific DescriptionThe protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The nuclear receptor RORalpha preserves cardiomyocyte mitochondrial function by regulating caveolin-3-mediated mitophagy. Beak JY et al., 2021 Dec, J Biol ChemRead more
- LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling. Luo J et al., 2019 Jun 12, Nat CommunRead more
- The nuclear receptor RORalpha protects against angiotensin II-induced cardiac hypertrophy and heart failure. Beak JY et al., 2019 Jan 1, Am J Physiol Heart Circ PhysiolRead more
- RORalpha and RORgamma expression inversely correlates with human melanoma progression. Brozyna AA et al., 2016 Sep 27, OncotargetRead more