Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ROR1 Polyclonal Antibody at dilution 1:35
ROR1 Polyclonal Antibody
E-AB-16872
Product group Antibodies
Overview
- SupplierElabscience
- Product NameROR1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThis gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
- UNSPSC12352203