RORgamma antagonist 1

TargetMol Chemicals

RORgamma antagonist 1

999

Chemical

Research Use Only

RORgamma antagonist 1

C35H60N2O2

540.86

RORgamma antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to RORgamma with a dissociation constant (K D) of 0.18 microM. It demonstrates anti-proliferative effects in the HPAF-II pancreatic cancer xenograft model, inhibits the RAS/MAPK and AKT/mTORC1 signaling pathways, and triggers caspase-dependent apoptosis in pancreatic cancer cells [1].

3 years

-20°C

12352200