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RORgammat inhibitor 3 [1361413-10-6]

HY-112863
MedChem Express
CAS Number1361413-10-6
Product group Chemicals
Molecular Weight559.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RORgammat inhibitor 3 [1361413-10-6]
  • Delivery Days Customer
    9
  • CAS Number
    1361413-10-6
  • Certification
    Research Use Only
  • Molecular Formula
    C26H20Cl2N2O4S2
  • Molecular Weight
    559.48
  • Scientific Description
    RORgammat inhibitor 3 is an orally active and potent retinoic acid receptor-related orphan receptor-gamma-t (RORgammat) inhibitor. RORgammat inhibitor 3 shows high binding affinity and inhibitory activity of Th17 cell differentiation. RORgammat inhibitor 3 also shows efficacy in both mouse experimental autoimmune encephalomyelitis (EAE) and collagen induced arthritis (CIA) models[1].
  • SMILES
    O=C(C1=C(Cl)C=CC=C1)C2=C(C3=CC(Cl)=CC=C3)N=C(NC(CC4=CC=C(S(=O)(CC)=O)C=C4)=O)S2
  • UNSPSC
    12352200