ROS 234

MedChem Express

ROS 234 [184576-87-2]

10

184576-87-2

Research Use Only

C13H15N5

241.29

ROS 234 is a potent H3 antagonist, with a pK B of 9.46 for Guinea-pig ileum H 3 -receptor, a pK i of 8.90 for Rat cerebral cortex H 3 -receptor, and a ED 50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access [1] [2] .

C1(NCCCC2=CN=CN2)=NC3=CC=CC=C3N1

12352200