ROS 234 (dioxalate) [1781941-93-2]

MedChem Express

ROS 234 (dioxalate) [1781941-93-2]

10

1781941-93-2

Research Use Only

C17H19N5O8

421.36

ROS 234 dioxalate is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 dioxalate diaplays poor central access[1][2].

O=C(O)C(O)=O.O=C(O)C(O)=O.C1(NCCCC2=CN=CN2)=NC3=CC=CC=C3N1

12352200