Rosiglitazone . maleate

AdipoGen Life Sciences

Rosiglitazone . maleate

10

155141-29-0

Research Use Only

>98%

C18H19N3O3S . C4H4O4

357.4 . 116.1

Chemical. CAS: 155141-29-0. Formula: C18H19N3O3S . C4H4O4. MW: 357.4 . 116.1. Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and vascular function. Enhances proliferation of endogenous neural progenitor cells (NPCs). Anti-inflammatory compound. Has controversial therapeutic effects on the cardiovascular system. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs). - Same activities as rosaglitazone (Prod. No. AG-CR1-3570) but different formulation. Antidiabetic, hypoglycemic agent [1, 5]. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist [2, 3]. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance [4-6, 8]. Improves blood pressure and vascular function [7]. Enhances proliferation of endogenous neural progenitor cells (NPCs) [9]. Anti-inflammatory compound [10, 11]. Has controversial therapeutic effects on the cardiovascular system [12]. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs) [13].

OC(=O)\C=C/C([O-])=O.C[NH+](CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1

2°C to 8°C

12352200