Rosiglitazone (maleate)

MedChem Express

Rosiglitazone (maleate) [155141-29-0]

5

155141-29-0

Research Use Only

99.88

C22H23N3O7S

473.50

Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARgamma , with EC 50 s of 30 nM, 100 nM and 60 nM for PPARgamma1 , PPARgamma2 , and PPARgamma , respectively, and a K d of appr 40 nM for PPARgamma ; Rosiglitazone maleate is also an modulator of TRP channels , inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5).

O=C(O)/C=C\C(O)=O.CN(CCOC1=CC=C(CC2C(NC(S2)=O)=O)C=C1)C3=CC=CC=N3

2°C to 8°C

12352200