Rosuvastatin (Calcium)

MedChem Express

Rosuvastatin (Calcium) [147098-20-2]

10

147098-20-2

Research Use Only

99.94

C22H27Ca0.5FN3O6S

500.57

Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC 50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC 50 of 195 nM [2] . Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels [1] [2] [3] .

O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]

2°C to 8°C

12352200