Rotundine [483-14-7]

MedChem Express

Rotundine [483-14-7]

10

483-14-7

Research Use Only

99.96

C21H25NO4

355.43

Rotundine is an antagonist of dopamine D1, D2 and D3 receptors with IC50s of 166 nM, 1.4 microM and 3.3 microM, respectively. Rotundine is also an antagonist of 5-HT1A with an IC50 of 370 nM.

COC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@]3([H])C2)=C1OC

-20°C,2°C to 8°C

12352200