RP 67580 [135911-02-3]

MedChem Express

RP 67580 [135911-02-3]

10

135911-02-3

Research Use Only

C29H30N2O2

438.56

RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation[1].

O=C1[C@@]2([H])CN(C(CC3=CC=CC=C3OC)=N)C[C@@]2([H])C(C4=CC=CC=C4)(C5=CC=CC=C5)CC1

12352200