Rp-Adenosine-5-O-(1-thiodiphosphate) sodium [2005478-89-5]

TargetMol Chemicals

Rp-Adenosine-5-O-(1-thiodiphosphate) sodium [2005478-89-5]

44

Chemical

Research Use Only

Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium

C10H12N5O9P2S.3Na

509.21

Rp-Adenosine-5-O-(1-thiodiphosphate) (Rp-ADP-alpha-S), a sulfur-containing isomer of the nucleotide derivative ADP-alpha-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 microM. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 microM and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 microM.

3 years

O[C@@H]1[C@@H](CO[P@](OP([O-])([O-])=O)([S-])=O)O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+]

-20°C

12352200