RPI-1

MedChem Express

RPI-1 [269730-03-2]

10

269730-03-2

99.29

C17H15NO4

297.31

RPI-1 is a specific, orally available 2-indolinone Ret tyrosine kinase inhibitor. RPI-1 inhibits proliferation, Ret tyrosine phosphorylation, Ret protein expression, and the activation of PLCgamma, ERKs and AKT in human medullary thyroid carcinoma TT cells. Antitumor activity [1] .

O=C1NC2=C(C=C(OC)C(OC)=C2)/C1=C/C3=CC=C(O)C=C3

-20°C,2°C to 8°C

12352200