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RPL3 antibody [N3C3]

GTX114725
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetRPL3
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPL3 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6122
  • Target name
    RPL3
  • Target description
    ribosomal protein L3
  • Target synonyms
    ASC-1, L3, TARBP-B, uL3, large ribosomal subunit protein uL3, 60S ribosomal protein L3, HIV-1 TAR RNA-binding protein B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP39023
  • Protein Name
    Large ribosomal subunit protein uL3
  • Scientific Description
    Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this genes introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Imai H, Utsumi D, Torihara H, et al. Simultaneous measurement of nascent transcriptome and translatome using 4-thiouridine metabolic RNA labeling and translating ribosome affinity purification. Nucleic Acids Res. 2023,51(14):e76. doi: 10.1093/nar/gkad545
    Read this paper
  • Watanabe S, Fujiyama H, Takafuji T, et al. GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system. J Cell Sci. 2018,131(15):pii: jcs213009. doi: 10.1242/jcs.213009.
    Read this paper
  • Shi J, Pabon K, Scotto KW. Methylxanthines Increase Expression of the Splicing Factor SRSF2 by Regulating Multiple Post-transcriptional Mechanisms. J Biol Chem. 2015,290(24):14986-5003. doi: 10.1074/jbc.M114.624254
    Read this paper