ProductsBack/RPRM antibody [N1C3]

RPRM antibody [N1C3]

Name: RPRM antibody [N1C3]
SKU: GTX110976_G10
Availability: BackOrder

GTX110976

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Product group Antibodies

ReactivityHuman, Mouse

TargetRPRM

Overview

Supplier
GeneTex
Product Name
RPRM antibody [N1C3]
Delivery Days Customer
9
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.71 mg/ml
Conjugate
Unconjugated
Gene ID56475
Target name
RPRM
Target description
reprimo, TP53 dependent G2 arrest mediator homolog
Target synonyms
candidate mediator of the p53 dependent G2 arrest; protein reprimo; REPRIMO; reprimo, TP53 dependant G2 arrest mediator candidate; reprimo, TP53 dependent G2 arrest mediator candidate
Host
Rabbit
Isotype
IgG
Protein IDQ9NS64
Protein Name
Protein reprimo
Scientific Description
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11.
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Hypothalamic estrogen receptor alpha establishes a sexually dimorphic regulatory node of energy expenditure. van Veen JE et al., 2020 Apr, Nat Metab
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Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells. Yan-Fang T et al., 2015, PLoS One
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