RPS6-IN-1
HY-161874
Molecular Weight433.31
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameRPS6-IN-1
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC16H18Cl2N4O4S
- Molecular Weight433.31
- Scientific DescriptionRPS6-IN-1 (Compound 22o) inhibits cell metastasis, induces cell apoptosis (increases the expression of Bax, p53, cleaved-caspase 3, and cleaved-PARP). RPS6-IN-1 decreases mitochondrial membrane potential. RPS6-IN-1 activates autophagy through the PI3K-Akt-mTOR signaling pathway, damages intracellular mitochondria and lysosomes, and cause ER stress. RPS6-IN-1 inhibits RPS6 phosphorylation. RPS6-IN-1 is an anticancer agent with low systemic toxicity[1].
- SMILESClC1=NC(Cl)=NC2=C1N=CN2C3(C(OCC)=O)CSC[C@H]3CC(OCC)=O
- UNSPSC12352200