Western blot analysis of extracts from HUVEC cells using MSK1(Ab-376) Antibody and the same antibody preincubated with blocking peptide.
Western blot analysis of extracts from HUVEC cells using MSK1(Ab-376) Antibody and the same antibody preincubated with blocking peptide.
RPS6KA5 (Ab-376) Antibody
CSB-PA144527
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetRPS6KA5
Overview
- SupplierCusabio
- Product NameRPS6KA5 (Ab-376) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9252
- Target nameRPS6KA5
- Target descriptionribosomal protein S6 kinase A5
- Target synonyms90 kDa ribosomal protein S6 kinase 5; MSK1; MSPK1; nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; RLPK; RSKL; RSK-like protein kinase; S6K-alpha-5
- HostRabbit
- IsotypeIgG
- Protein IDO75582
- Protein NameRibosomal protein S6 kinase alpha-5
- Scientific DescriptionSerine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of Ser-1 of histone H2A. Phosphorylates Ser-10 of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate Ser-28 of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14). Roux PP, et al. (2004) Microbiol Mol Biol Rev. Jun; 68(2): 320-344 McCOY C, et al. (2005) Biochem J. Apr 15; 387(Pt 2): 507-517
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203