RPUSD4 Antibody

Cusabio

RPUSD4 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RPUSD4

RNA pseudouridine synthase D4

pseudouridylate synthase RPUSD4, mitochondrial, RNA pseudouridylate synthase domain containing 4, RNA pseudouridylate synthase domain-containing protein 4, mitochondrial RNA pseudouridine synthase RPUSD4

Rabbit

IgG

Pseudouridylate synthase RPUSD4, mitochondrial

Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome (PubMed:27974379). Acts on position 39 in mitochondrial tRNA(Phe) (PubMed:28082677). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).

Human

-20°C or -80°C

41116161