(R,R)-GSK321 [1816272-19-1]

MedChem Express

(R,R)-GSK321 [1816272-19-1]

10

1816272-19-1

Research Use Only

99.36

C28H28FN5O3

501.55

(R,R)-GSK321 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. (R,R)-GSK321 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity[1].

O=C(C1=NN(CC2=CC=C(F)C=C2)C3=C1CN(C(C4=CC=CN4)=O)C[C@H]3C)NC5=CC=CC([C@H](O)C)=C5

-20°C,2°C to 8°C

12352200