RRX-001

AbMole BioScience

RRX-001

9

925206-65-1

Chemical

Research Use Only

C5H6BrN3O5

268.02

Rrx-001 is a hypoxic selective epigenetic factor that has been used as a radiation or chemotherapy sensitizer to induce apoptosis. Rrx-001 is an immune checkpoint inhibitor that down-regulates CD47 and SIRP-alfa. Rrx-001 is also an effective inhibitor of G6PD with strong antimalarial activity. Rrx-001 inhibits the expression of CD47 in tumor cells by inhibiting c-myC, a positive regulator of CD47.

[O-][N+](=O)C1(CN(C1)C(=O)CBr)[N+]([O-])=O

12352200