RS-25344 (hydrochloride) [152815-28-6]

MedChem Express

RS-25344 (hydrochloride) [152815-28-6]

10

152815-28-6

Research Use Only

99.93

C19H14ClN5O4

411.80

RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0.28 nM in human lymphocytes. RS-25344 hydrochloride has only weak inhibitory effects on PDE I, II, III (IC50 of >100 microM, 160 microM, 330 microM, respectively). RS-25344 hydrochloride has anti-inflammatory, memory- and cognition enhancing, and antineoplastic effects[1][2].

[H]Cl.O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O

2°C to 8°C

12352200