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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA644834DSR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA644834DSR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA644834DSR1HU at dilution of 1:100

RSPO1 Antibody

CSB-PA644834DSR1HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRSPO1
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Overview

  • Supplier
    Cusabio
  • Product Name
    RSPO1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID284654
  • Target name
    RSPO1
  • Target description
    R-spondin 1
  • Target synonyms
    CRISTIN3; roof plate-specific spondin-1; RSPO; R-spondin homolog; R-spondin-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ2MKA7
  • Protein Name
    R-spondin-1
  • Scientific Description
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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