Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA887154LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA887154LA01HU at dilution of 1:100
RSPO3 Antibody
CSB-PA887154LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRSPO3
Overview
- SupplierCusabio
- Product NameRSPO3 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID84870
- Target nameRSPO3
- Target descriptionR-spondin 3
- Target synonymsCRISTIN1; protein with TSP type-1 repeat; PWTSR; roof plate-specific spondin-3; R-spondin 3 homolog; R-spondin-3; thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; THSD2
- HostRabbit
- IsotypeIgG
- Protein IDQ9BXY4
- Protein NameR-spondin-3
- Scientific DescriptionActivator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203