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Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA887154LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA887154LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA887154LA01HU at dilution of 1:100

RSPO3 Antibody

CSB-PA887154LA01HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetRSPO3
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Overview

  • Supplier
    Cusabio
  • Product Name
    RSPO3 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID84870
  • Target name
    RSPO3
  • Target description
    R-spondin 3
  • Target synonyms
    CRISTIN1; protein with TSP type-1 repeat; PWTSR; roof plate-specific spondin-3; R-spondin 3 homolog; R-spondin-3; thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; THSD2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BXY4
  • Protein Name
    R-spondin-3
  • Scientific Description
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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