RSV L-protein-IN-1 [851658-10-1]

MedChem Express

RSV L-protein-IN-1 [851658-10-1]

14

851658-10-1

Research Use Only

98.09

C32H36N6O6

600.66

RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 microM). RSV L-protein-IN-1 inhibits Polymerase (IC50=0.089 microM), and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 microM, HEp-2), also exhibits activity and lowers virus titers in mouse models of RSV infection[1].

O=C(C(C)(C)C1=C2C3=C(NC(C4=CC=C(C)C([N+]([O-])=O)=C4)=N3)C(N)=C1)N(CCCNCCC5=CC=C(OC)C(OC)=C5)C2=O

-20°C

12352200