RTICBM-189

MedChem Express

RTICBM-189 [551909-15-0]

10

551909-15-0

Research Use Only

99.73

C15H14Cl2N2O

309.19

RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay. RTICBM-189 has pIC50s of 5.29 and 6.25 for hCB1 and mCB1, respectively. RTICBM-189 significantly and selectively attenuates the reinstatement of the addictive agent-seeking behavior in rats[1].

O=C(NCCC1=CC(Cl)=CC=C1)NC2=CC=C(C=C2)Cl

2°C to 8°C

12352200