RTN4RL2 Antibody

Cusabio

RTN4RL2 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

RTN4RL2

reticulon 4 receptor like 2

NGRH1, NgR2, reticulon-4 receptor-like 2, Nogo-66 receptor homolog 1, nogo receptor-like 3, nogo-66 receptor-related protein 2

Rabbit

IgG

Reticulon-4 receptor-like 2

Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).

Human

-20°C or -80°C

41116161