RU.521
HY-114180
CAS Number2262452-06-0
Product group Chemicals
Estimated Purity99.95
Molecular Weight415.23
Overview
- SupplierMedChem Express
- Product NameRU.521 [2262452-06-0]
- Delivery Days Customer10
- CAS Number2262452-06-0
- CertificationResearch Use Only
- Estimated Purity99.95
- Molecular FormulaC19H12Cl2N4O3
- Molecular Weight415.23
- Scientific DescriptionRU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC 50 of 0.7 microM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutires syndrome (AGS) [1] .
- SMILESO=C1OC(C2=C(O)N(C3=NC4=CC=C(Cl)C(Cl)=C4N3)N=C2C)C5=C1C=CC=C5
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200