Ruboxistaurin hydrochloride

Bioss

Ruboxistaurin hydrochloride

16

Research Use Only

98.0

Ruboxistaurin hydrochloride, also known as LY-333531 hydrochloride, is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-beta1/Smad and GRAP pathways. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin inhibits retinal neovascularization via suppression of phosphorylation of ERK1/2 and Akt.

-20°C

51202000