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ProductsBack/Rubratoxin A [22467-31-8]
Chemical Structure
Chemical Structure
Chemical Structure

Rubratoxin A [22467-31-8]

Research Use Only
AG-CN2-0092
AdipoGen Life Sciences
CAS Number22467-31-8
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight520.2
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Rubratoxin A
  • Delivery Days Customer
    10
  • CAS Number
    22467-31-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C26H32O11
  • Molecular Weight
    520.2
  • Scientific Description
    Chemical. CAS: 22467-31-8. Formula: C26H32O11. MW: 520.2. Isolated from Penicillium sp. Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic. - Mycotoxin [1]. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP [2]. Antitumor agent. Antimetastatic [2].
  • SMILES
    [H][C@]1(CC=CC(=O)O1)[C@@H](O)[C@@]1([H])CC2=C(C(=O)OC2O)[C@@]([H])([C@H](O)CCCCCC)[C@H](O)C2=C(C1)C(=O)OC2=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • The structure of rubratoxin A, a toxic metabolite of Penicillium rebrum: M.O. Moss, et al.; Tetrahedron Lett. 5, 367 (1969)
  • Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis: S. Wada, et al.; Cancer Sci. 101, 743 (2010)