Rucaparib (phosphate)

MedChem Express

Rucaparib (phosphate) [459868-92-9]

10

459868-92-9

Research Use Only

99.76

C19H21FN3O5P

421.36

Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4] .

O=P(O)(O)O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1

2°C to 8°C

12352200