Ruplizumab [220651-94-5]

MedChem Express

Ruplizumab [220651-94-5]

10

220651-94-5

Research Use Only

Monoclonal

99.84

Ruplizumab (BG 9588) is a humanized anti-CD40L IgG1kappa monoclonal antibody. By binding to CD40L, Ruplizumab blocks its interaction with the CD40 receptor, inhibits T-B cell costimulatory signals, and mediates the depletion of activated T cells via the Fc segment. Ruplizumab has immunosuppressive effects. Ruplizumab can be used in the study of systemic lupus erythematosus, organ transplant rejection, and autoimmune diseases. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1][2].

-80°C

41116161