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Ruxolitinib Phosphate

S5243
Selleck Chemicals
CAS Number1092939-17-7
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Ruxolitinib Phosphate [1092939-17-7]
  • Delivery Days Customer
    9
  • CAS Number
    1092939-17-7
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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