Ruxolitinib, Phosphate [1092939-17-7]

BPS Bioscience

Ruxolitinib, Phosphate

7

1092939-17-7

Research Use Only

≥99%

C17H18N6 H3O4P

404.3 Da

Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.

-20°C

51202000