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Ruxolitinib, Phosphate [1092939-17-7]

Research Use Only
27059
BPS Bioscience
CAS Number1092939-17-7
Product group Chemicals
Estimated Purity≥99%
Molecular Weight404.3 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Ruxolitinib, Phosphate
  • Delivery Days Customer
    7
  • CAS Number
    1092939-17-7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Molecular Formula
    C17H18N6 H3O4P
  • Molecular Weight
    404.3 Da
  • Scientific Description
    Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000