Ruxolitinib, Phosphate [1092939-17-7]
27059
CAS Number1092939-17-7
Product group Chemicals
Estimated Purity≥99%
Molecular Weight404.3 Da
Overview
- SupplierBPS Bioscience
- Product NameRuxolitinib, Phosphate
- Delivery Days Customer7
- CAS Number1092939-17-7
- CertificationResearch Use Only
- Estimated Purity≥99%
- Molecular FormulaC17H18N6 H3O4P
- Molecular Weight404.3 Da
- Scientific DescriptionRuxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.
- Storage Instruction-20°C
- UNSPSC51202000