RV gE1 Mosaic (residues 157-176/374-390/213-239), Rubella Virus Glycoprotein E1, recombinant, E. coli

Jena Bioscience

RV gE1 Mosaic (residues 157-176/374-390/213-239), Rubella Virus Glycoprotein E1, recombinant, E. coli

5

Western Blot, ELISA

Research Use Only

>95%

The protein contains glycoprotein E1 immunodominant fragments, amino acids: 157-176, 213-239, and 374-390. The protein is purified by proprietary chromatographic technique. Background: Rubella virus is an enveloped positivestrand RNA virus of the family TOGAVIRIDAE. The genome encodes two open reading frames (ORFs): the 5-proximal ORF encodes viral nonstructural proteins (NSP) that are responsible for viral genome replication, while the 3-proximal ORF encodes three virion structural proteins (SP), the capsid protein (CP), and the two envelope glycoproteins, E2 and E1. During virus assembly, the capsid interacts with genomic RNA to form nucleocapsids. The rubella virus (RV) structural proteins: capsid, E2, and E1 are synthesized as a polyprotein precursor. The signal peptide that initiates translocation of E2 into the lumen of the endoplasmic reticulum remains attached to the carboxy terminus of the capsid protein after cleavage by signal peptidase.

-20°C

12352202