RVX-297 [1044871-04-6]
HY-114504
CAS Number1044871-04-6
Product group Chemicals
Estimated Purity96.59%
Molecular Weight423.5
Overview
- SupplierMedChem Express
- Product NameRVX-297 [1044871-04-6]
- Delivery Days Customer5
- CAS Number1044871-04-6
- CertificationResearch Use Only
- Estimated Purity96.59%
- Molecular FormulaC24H29N3O4
- Molecular Weight423.5
- Scientific DescriptionRVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 microM for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 is effective in acute inflammation and autoimmunity models.
- SMILESO=C1NC(C2=CC(C)=C(OCCN3CCCC3)C(C)=C2)=NC4=C1C(OC)=CC(OC)=C4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200