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RWJ-56110

HY-108556
MedChem Express
CAS Number252889-88-6
DownloadMSDS
Product group Chemicals
Molecular Weight790.73
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RWJ-56110 [252889-88-6]
  • Delivery Days Customer
    10
  • CAS Number
    252889-88-6
  • Certification
    Research Use Only
  • Molecular Formula
    C41H43Cl2F2N7O3
  • Molecular Weight
    790.73
  • Scientific Description
    RWJ-56110 is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC 50 =0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 inhibits the aggregation of human platelets induced by?both?SFLLRN-NH2?( IC 50 =0.16 microM) and thrombin ( IC 50 =0.34 microM), quite selective?relative to U46619 (HY-108566). RWJ-56110 inhibits angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 induces cell apoptosis [1] [2] .
  • SMILES
    O=C(N[C@H](C(NCC1=CC=CC=C1)=O)CCN)[C@@H](NC(NC2=CC3=C(C=C2)C(CN4CCCC4)=CN3CC5=C(Cl)C=CC=C5Cl)=O)CC6=CC=C(F)C(F)=C6
  • UNSPSC
    12352200