RWJ-67657

MedChem Express

RWJ-67657 [215303-72-3]

10

215303-72-3

Research Use Only

99.75

C27H24FN3O

425.50

RWJ-67657 (JNJ 3026582) is an orally active and selective p38alpha and p38beta MAPK inhibitor with IC 50 s of 1 and 11 microM, respectively. RWJ-67657 displays no activity at p38gamma and p38delta, and exhibits cardio protective effect. Anti-inflammatory and anti-tumor activity [1] .

OCCC#CC1=NC(C2=CC=C(F)C=C2)=C(C3=CC=NC=C3)N1CCCC4=CC=CC=C4

-20°C,2°C to 8°C

12352200