RWJ52353

MedChem Express

RWJ52353 [245744-10-9]

5

245744-10-9

Research Use Only

C11H10N2S

202.28

RWJ52353 is a selective, orally active ligand for alpha2D adrenoceptor, which binds alpha2D, alpha2A, alpha2B and alpha1 receptors, with K i s of 1.5, 254, 621 and 443 nM. RWJ52353 exhibits analgesic efficacy in mouse abdominal irritation test (MAIT), with an ED 50 of 15.1 mg/kg [1] .

C1(C2=CCCC3=C2C=CS3)=CN=CN1

12352200