RWJ52353

MedChem Express

RWJ52353

5

245744-10-9

Research Use Only

C11H10N2S

202.28

RWJ52353 is a selective, orally active ligand for alpha2D adrenoceptor, which binds alpha2D, alpha2A, alpha2B and alpha1 receptors, with Kis of 1.5, 254, 621 and 443 nM. RWJ52353 exhibits analgesic efficacy in mouse abdominal irritation test (MAIT), with an ED50 of 15.1 mg/kg[1].

C1(C2=CCCC3=C2C=CS3)=CN=CN1

12352200