Ryuvidine

MedChem Express

Ryuvidine [265312-55-8]

10

265312-55-8

99.40

C15H12N2O2S

284.33

Ryuvidine is a potent inhibitor of SET domain-containing protein 8(SETD8) with an IC 50 of 0.5 microM and suppresses monomethylation of H 4 K 20 . Ryuvidine also inhibits CDK4 with an IC 50 of 6.0 microM. Ryuvidine also inhibits KDM5A and blocks DNA synthesis. Ryuvidine has anticancer activity against tumors such as breast cancer. Ryuvidine improves arthritis [1] [2] [3] [4] [5] .

O=C1C=C(C(C2=C1SC(C)=N2)=O)NC3=CC=C(C)C=C3

-20°C,2°C to 8°C

12352200