S-22153 [180304-07-8]

MedChem Express

S-22153 [180304-07-8]

10

180304-07-8

Research Use Only

99.88

C14H17NOS

247.36

S-22153 is a potent melatonin receptor antagonist with EC50 values of 19 nM, 4.6 nM for hMT1 and hMT2 melatonin receptor, respectively. S-22153 has Ki values of 8.6 nM (CHO cells) and 16.3 nM (HEK cells) for hMT1, and 6.0 nM (CHO cells) and 8.2 nM (HEK cells) for hMT2. S-22153 is a specific ligand of MT1 and MT2 melatonin receptors subtypes[1][2].

CC(NCCC1=CSC2=CC=C(C=C12)CC)=O

-20°C,2°C to 8°C

12352200