(S)-AZD 6482 [1173900-37-2]

MedChem Express

(S)-AZD 6482 [1173900-37-2]

5

1173900-37-2

Research Use Only

C22H24N4O4

408.45

(S)-AZD6482 ((S)-KIN-193) is a highly effective and selective ATP-competitive inhibitor of PI3Kbeta, exhibiting an IC(50) of 0.01 microM, and it can reduce insulin-induced glucose uptake by human adipocytes in vitro with an IC(50) of 4.4 microM.

O=C(C1=CC=CC=C1N[C@@H](C)C2=CC(C)=CN3C2=NC(N4CCOCC4)=CC3=O)O

12352200