(S)-BI 2536 [1241725-90-5]

TargetMol Chemicals

(S)-BI 2536 [1241725-90-5]

9

Research Use Only

C28H39N7O3

521.66

(S)-BI 2536 serves as a dual inhibitor, targeting both PLK1 kinase and the BRD4 bromodomain, with Ki values of 0.42 nM and 54 nM, respectively. It is recognized as the less active enantiomer of BI 2536.

C(C)[C@@H]1N(C=2C(N(C)C1=O)=CN=C(NC3=C(OC)C=C(C(NC4CCN(C)CC4)=O)C=C3)N2)C5CCCC5

-20°C

12352200