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(S)-CR8 [1084893-56-0]

HY-112371
MedChem Express
CAS Number1084893-56-0
Product group Chemicals
Estimated Purity99.0
Molecular Weight431.53
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (S)-CR8 [1084893-56-0]
  • Delivery Days Customer
    5
  • CAS Number
    1084893-56-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C24H29N7O
  • Molecular Weight
    431.53
  • Scientific Description
    (S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 microM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 microM)[1].
  • SMILES
    CC[C@H](NC1=NC(NCC2=CC=C(C3=NC=CC=C3)C=C2)=C4N=CN(C(C)C)C4=N1)CO
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200