(S)-(+)-Dimethindene (maleate)

MedChem Express

(S)-(+)-Dimethindene (maleate) [136152-65-3]

10

136152-65-3

Research Use Only

99.94

C24H28N2O4

408.49

(S)-(+)-Dimethindene maleate, an enantiomer, is a potent M 2 -selective muscarinic receptor antagonist ( pA 2 = 7.86/7.74; pK i = 7.78). (S)-(+)-Dimethindene maleate shows lower affinities for the muscarinic M 1 (pA 2 = 6.83/6.36; pK i = 7.08), the M 3 (pA 2 = 6.92/6.96; pK i = 6.70) and the M 4 receptors (pK i = 7.00), respectively. (S)-(+)-Dimethindene maleate also is a histamine H 1 receptor antagonist ( pA 2 = 7.48) [1] .

C[C@@H](C1=C(CCN(C)C)CC2=C1C=CC=C2)C3=NC=CC=C3.OC(/C=C\C(O)=O)=O

2°C to 8°C

12352200