(S)-ML188 [1417700-12-9]

MedChem Express

(S)-ML188 [1417700-12-9]

5

Research Use Only

C26H31N3O3

433.54

(S)-ML188 is a SARS-CoV 3-chymotrypsin-like protease (3CLpro) inhibitor (IC50: 1.5 microM). (S)-ML188 has antiviral activity with an EC50 value of 12.9 microM against SARS-CoV. (S)-ML188 inhibits the activity of 3CLpro via non-covalent binding and can be used in the study of SARS-CoV[1].

CC(C)(NC([C@H](C1=CC=CN=C1)N(C2=CC=C(C(C)(C)C)C=C2)C(C3=CC=CO3)=O)=O)C

12352200