(S)-Monastrol [254753-54-3]

MedChem Express

(S)-Monastrol [254753-54-3]

5

254753-54-3

Research Use Only

C14H16N2O3S

292.35

(S)-Monastrol ((+)-Monastrol) is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cancer cell lines. (S)-Monastrol arrests mammalian cells in mitosis with monopolar spindles[1][2].

O=C(C1=C(C)NC(N[C@H]1C2=CC=CC(O)=C2)=S)OCC

12352200