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(S)-p38 MAPK Inhibitor III [581098-48-8]

Research Use Only
T35420
TargetMol Chemicals
CAS Number581098-48-8
Product group Chemicals
Molecular Weight404.5
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (S)-p38 MAPK Inhibitor III [581098-48-8]
  • Delivery Days Customer
    44
  • CAS Number
    581098-48-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    (S)-p38 MAPK Inhibitor III
  • Molecular Formula
    C23H21FN4S
  • Molecular Weight
    404.5
  • Scientific Description
    (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 microM in vitro). It is cell-permeable, potently blocking the release of TNF-alpha and IL-1beta from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 microM, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    S(C)C=1NC(=C(N1)C=2C=C(N[C@@H](C)C3=CC=CC=C3)N=CC2)C4=CC=C(F)C=C4
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000